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Contact Info
Dr. M Jhansi Lakshmi
7780335763
Department of Zoology, School of Basic Sciences.
Dr. M Jhansi Lakshmi

Assistant Professor,

Department of Zoology,

School of Basic Sciences.

Qualification

Examination

Year

Board/ University

Ph.D.

2020

University of Texas Health Science Center at Tyler (UTHCT)/JSS AHER

M.Sc. (Zoology)

2013

University of Mysore (UOM)

B. Sc.Ed Zoology

2011

NCERT-Regional Institute of education (RIE)

Experience
Teaching Experience

Designation

 Institute

 From

 To

Assistant Professor

Central University of Punjab

May 2024

Till date

Ramanujan Fellow equivalent to scientist D

ICMR-National Institute of Nutrition (NIN)

June 2023

May 2024

Research Experience

Designation

 Institute

 From

 To

Assistant Professor

Central University of Punjab

May 2024

Till date

Ramanujan Fellow equivalent to scientist D

ICMR-National Institute of Nutrition (NIN)

June 2023

May 2024

Postdoctoral Research

University of Texas Health Science Center at Tyler (UTHCT)

2020

2022

Ph.D.

University of Texas Health Science Center at Tyler (UTHCT)/JSS AHER

2016

2020

Administrative Experience
 
Any Other Experience

 

Research Area

Biomedical sciences 

Research Interests

Cardiovascular Biology, Cellular and Molecular biology

Biochemistry

Inflammation and Cell signaling

Immunology

 

Research Grants/Projects

Name of the grant

Awarding agency  

Fund

From

To

Prestigious Ramanujan fellowship

DST- SERB, government of India.

1.35 crore rupees

2023

2028

Judith  Graham

Pool     Post- Doctoral Fellowship

The National Haemophilia Foundation

(NHF),USA.

$ 1,04, 000

2020

2022

Sponsored research fellowship

The University of Texas at Tyler,

Texas, USA

$ 1,40,000

2016

2020

Professional Recognition/Awards/Scholarships

1. Prestigious Ramanujan Fellowship, Division of Maternal and Child Health & Nutrition ICMR- National Institute of Nutrition (ICMR-NIN), DHR, MoHFW, GOI. Grant amount (1.35 crore), 2023-2028 from DST-SERB, government of India.

2. Judith Graham Pool (JGP) postdoctoral grant ($52,000 per annum) awarded by National Hemophilia Foundation (NHF), 2020-2022, USA.

3. Abstract Achievement Award from American Society of Hematology (ASH), Orlando, 2019, USA.

4. Travel support from Gordon Research Conference (GRC), 2018, USA.

5. Sponsored research Fellowship for Ph.D. program at The University of Texas Health Science Centre at Tyler (UTHSCT), 2016-2020, USA.

Publications
Papers
  1. Jhansi L Magisetty, Gadiraju B, Kondreddy V. Genomic analysis in the colon tissues of omega-3 fatty acid-treated rats identifies novel gene signatures implicated in ulcerative colitis. Int J Biol Macromol. Published online December 19, 2023.1PMID 28867. Impact factor 8.2
  2. Kaushik Das, Shiva Keshava, Tanmoy Mukherjee, Jue Wang, JhansiMagisetty, Richard Kolesnick, Usha R. Pendurthi, L. Vijaya Mohan Rao. Factor VIIa releases              phosphatidylserine enriched EVs from endothelial cells by activating acid sphingomyelinase. Journal of thrombosis and hemostasis (JTH), 2023, impact factor 16.0 
  3. Kondreddy V, Keshava S, Das K, Jhansi L Magisetty, Rao LVM, Pendurthi UR. The Gab2- MALT1 axis regulates thromboinflammation and deep vein thrombosis.             Blood. 2022 Sep 29;140(13):1549-1564. doi: 10.1182/blood.2022016424. PMID: 35895897. Impact Factor: 25.6
  4. Jhansi L Magisetty, Kondreddy VKR, Keshava S, Das K, Esmon C, Pendurthi UR, Rao LVM. Selective inhibition of activated protein C anticoagulant activity protects against hemophilic arthropathy. BLOOD, 2022 Feb 10: blood.2021013119. doi: 10.1182/blood.2021013119. Epub ahead of print. PMID: 35143636. Impact Factor: 25.6
  5. Vijay Kondreddy, Jhansi L Magisetty, Shiva Keshava, L. Vijaya Mohan Rao, UshaR. Pendurthi. Gab2 (Grb2-Associated Binder2) Plays a Crucial Role in Inflammatory Signaling and Endothelial Dysfunction. Arterioscler Thromb Vasc Biol. 2021 Jun;41(6):1987-2005. doi:    10.1161/ATVBAHA.121.316153.    Epub    2021    Apr    8. PMID: 33827252.
  6. Keshava S, Jhansi L Magisetty, Tucker TA, Kujur W, Mulik S, Esmon CT, Idell S, Rao LVM, Pendurthi UR. Endothelial Cell Protein C Receptor Deficiency Attenuates Streptococcuspneumoniae-induced Pleural Fibrosis. Am J Respir Cell Mol Biol. 2021 Apr;64(4):477-491. doi: 10.1165/rcmb.2020-0328OC. PMID: 33600743.
  7. Jhansi L Magisetty, Usha R. Pendurthi, Charles T Esmon, L. Vijaya Mohan Rao. EPCR deficiency or function-blocking antibody protects against joint bleeding– induced pathology in hemophilia mice. BLOOD, 2020, 135 (25): 2211–2223.
  8. Jhansi L Magisetty, Usha R. Pendurthi, Subbarao V. Madhunapantula, Jerry Grandoni, L. Vijaya Mohan Rao. Increased Accumulation and Retention of rhFVIIa (eptacog beta) in Knee Joints of Hemophilia A Mice Compared to Wild-type Mice. Thromb Haemost 2019; 119(08): 1283-1294 DOI: 10.1055/s-0039-1688907.
  9. Jhansi L Magisetty, Sowmya shree G, Sharavana G, Sathaiah G, Sreerama YN, Baskaran.V.Lactucaxanthin - a potential anti-diabetic carotenoid from lettuce (Lactuca sativa) inhibits α- amylase and α-glucosidase activity in vitro and in diabetic rats. Food and function. 2017 Mar 22;8(3):1124-1131.
  10. Obulesu M and Jhansi L Magisetty, Neuroprotective Role of Nanoparticles Against Alzheimer's Disease. Current Drug Metabolism 2016; 17, 142-149.
  11. Obulesu M, Jhansi L Magisetty, Neuroinflammation in Alzheimer’s Disease: An understanding of physiology and pathology. International Journal of Neuroscience 2014;227-235.
  12. Obulesu, M., Jhansi L Magisetty. Apoptosis in Alzheimer’s Disease: An Understanding of Physiology, Pathology a Physiology Avenues. Neurochem Res 39, 2301–2312 (2014). https://doi.org/10.1007/s11064-014-1454-4
  13. Anirudh R. Acharya, Jhansi L Magisetty, Morphometric Variations in Mysore City Populations of Culex quinquefasciatus (Say) Larvae. Advances in Zoology and 2013 Botany, 1(1): 1-6.
  14. Anirudh R. Acharya, Jhansi L Magisetty, Adarsha Chandra V.R, Chaithra B.S, Taiyaba Khanum and Vijayan V.A, (2013), Trend of malaria incidence in the state of Karnataka,India for 2001 to 2011. Archives of Applied Science Research, 2013, 5 (3):104-111.
Articles
 
Books
 
Book Chapters
  1. Obulesu M, and Jhansi Magisetty, "Liposomes in apoptosis induction and cancer therapy." Apoptosis Methods in Toxicology (2016): 231-237.
 
Tools/Tests

 

Conference/ Workshops/Seminars Attended
University Level
 
National

1. Abdul Majid, Jhansi L Magisetty, Poornima Priyadarshini, Targeting Dipeptidyl peptidase-4 (DPP4) by peptide inhibitors for the management of Type-2 diabetes.

2. Jhansi L Magisetty & Baskaran V. Lactucaxanthin - a potential anti-diabetic carotenoid from lettuce (Lactuca sativa) .7 th International Food Convention (IFCON) 18 -21 DEC-2013, CSIR-CFTRI, Mysore, India.

3. Jhansi L Magisetty, “Lead (Pb) induced DNA damage in Alzheimer’s disease. Oral Presentation at National conference on recent advances in molecular and immuno diagnostics; organized by Aurora Degree and PG college on 22 and 23 rd. February 2013,Hyderabad, India. Won Best Oral Presentation Award.

International

1. Jhansi L Magisetty Usha R. Pendurthi, Charles T Esmon, L. Vijaya Mohan Rao. Abstract published online, EPCR deficiency prevents the development of hemophilic arthropathy. BLOOD 2019, 134 (Supplement-1): 159. 61st American Society of Hematology (ASH) meeting, Orlando, FL, USA. Selected for oral presentation (meritorious top 5% abstracts are selected). Won Abstract Achievement Award.

2. Jhansi L Magisetty, Usha R. Pendurthi, Subbarao V. Madhunapantula, Jerry Grandoni, L. Vijaya Mohan Rao. Increased Accumulation and Retention of rhFVIIa (eptacog beta) in Knee Joints of Hemophilia A Mice Compared to Wild-type Mice. Gordon Research Conference on Hemostasis 2018, Waterville Valley, New Hampshire, USA.

Invited Talks/ Resource Person
• Jhansi Magisetty was invited speaker at st. Josephs college for women, Vishakapatnam. Delivered lecture about Health and Nutrition in adolescents on 2nd September 2023.
Patent Filed/ Published
PATENT FILED

Jhansi L Magisetty, Usha Pendurthi, Rao LVM. Treatment and prevention of hemophilic arthropathy with an antibody against endothelial protein C receptor (EPCR)US Serial No: 17/273,965     Filing Date: March 5 2021. Patent Filed by: Board of Regents, The University of Texas System.