Dr. Sabyasachi Senapati

Contact Info
Dr. Sabyasachi Senapati
Immunogenomics Laboratory. Lab. No. 312.
Dr. Sabyasachi Senapati

Assistant Professor
Department of Human Genetics and Molecular Medicine
School of Health Sciences

Qualification
      Degree               Subject area                 University
PhD (2013) Genetics University of Delhi
M.Phil (2008) Molecular Endocrinology University of Delhi
M.Sc (2007) Zoology (Genetics) University of Delhi
B.Sc (2005) Zoology University of Calcutta
Experience

Teaching Experience

  • Assistant Professor (2015 – till date): Department of Human Genetics and Molecular Medicine, Central University of Punjab, Bathinda, India
  • Assistant Professor (2014 –2015): Department of Zoology, Ramjas College, University of Delhi, Delhi, India

Research Experience

  • Principal Investigator (Aug 2015 – till date): Immunogenomics Laboratory, Department of Human Genetics and Molecular Medicine, Central University of Punjab, Bathinda, India
  • Visiting PhD Fellow (Mar 2011 – Sept 2011): Department of Human Genetics, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands

Institutional Administrative Experience

  • Innovation Ambassador of the Institutional Innovation Council (IIC), Central University of Punjab, Bathinda 
  • Member of the Institutional Innovation Council (IIC), Central University of Punjab, Bathinda. 
  • Member, Institutional Ethics Committee (IEC), 2016-2021, Central University of Punjab
  • Program Officer, NSS, Central University of Punjab
  • Member, Board of Studies (BOS), Department of Human Genetics & Molecular Medicine, Central University of Punjab
  • Member, School Board, School of Health Sciences, Central University of Punjab
  • Member, Academic and Administrative Committee (AAC), Department of Human Genetics & Molecular Medicine, Central University of Punjab
  • Member, Curriculum Development Committee (CDC), Department of Human Genetics & Molecular Medicine, Central University of Punjab
  • Departmental coordinator for Alumni relations, Department of Human Genetics & Molecular Medicine, Central University of Punjab
  • Departmental coordinator for Placement Cell, Department of Human Genetics & Molecular Medicine, Central University of Punjab

National Experience

  • Executive Council (EC) Member of the Indian Society of Human Genetics (ISHG). 2023-2025. 
Research Area

Specific areas of interest are:

  • Genetics and genomics of common and rare diseases
  • HLA typing and immunogenomics  
  • Genetic epidemiology and Public health research on vitamin D deficiency and celiac disease (wheat allergy) 
  • Functional genomics
  • Stem cell biology

Presently the laboratory is focusing on understanding the genetics of autoimmune diseases, such as celiac disease, granulomatosis with polyangiitis (GPA, systemic small blood vessel vasculitis), chronic obstructive pulmonary disease (COPD), vitamin D deficiency (VDD) and SARS-CoV-2 infection in human. 

 

Contribution to Policy Documents (Govt. of India):

1. ICMR Guideline on diagnosis & management of celiac disease (https://main.icmr.nic.in/sites/default/files/guidelines/ICMR%20-%20Diag…)

Research Interests

RI1RI2RI3RI4

Research Grants/Projects
Sr. No. Projects Role Funding agency (Duration) Grant Sanctioned
1.

Celiac disease gene expression study

 PI

Central University of Punjab - Research Seed Money

(2016-2018)

 3 L
2.

Celiac disease genetic association study

 PI

University Grant Commission - BRS

(2017-2019)

 6 L
3.

Tissue specific gene expression regulation in celiac disease

 PI

DST- Science & Engineering Research Board (DST) - Early Career Research Grant

(2017-2020)

 46.5 L
4.

Celiac disease functional genomics

 Mentor

DST Women Scientist-A research grant (to Ms. Nidhi Sharma)

(2019-2022)

 25 L
5.

Primordial Dwarfism (Pd) in Indian Patients

 Co-PI

ICMR - Task Force for Rare Disorders

(2020-2023)

 40 L
6. 

Immunogenomics of Granulomatosis with Polyangiitis (GPA)

 PI

ICMR - Task Force for Rare Disorders

(2020-2023)

 70 L
7. Breast cancer therapeutics  Co-PI

ICMR 

(2021-2024)

 41 L
8. DST-PURSE Project  Group Member

DST

(2023-2027)

 882 L
9. Evidence Synthesis for Lung Cancer Guidelines: Conducting Systematic Reviews/meta-analysis. Co-PI

ICMR

(2024)

 5.13 L

 

Professional Affiliation
  • Life Member of Indian Society of Human Genetics (ISHG), Hyderabad, India
  • Life Member of Indian Society of Cell Biology (ISCB), Varanasi, India
  • Life Member of International Society for Study of Celiac Disease (ISSCD), Hague, Netherlands.
Professional Recognition/Awards/Scholarships
  • Member of the Executive Council (EC) of the Indian Society of Human Genetics (ISHG), 2023 onwards
  • Young Scientist Travel Award, International Congress of Human Genetics, April. 2016, Kyoto, Japan.
  • Young Scientist Award, Association of Biotechnology & Pharmacy, Oct. 2013, New Delhi, India.
  • Visiting graduate student fellowship (Mar 2011– Sept 2011) by University Medical Centre Groningen, Groningen, The Netherlands.
  • CSIR Junior research fellowship (Dec. 2007; Jun. 2008)
  • Qualified for prestigious Dr. Shyama Prasad Mukherjee  (SPM) Fellowship selecton - CSIR, Dec. 2007 and June 2008
Research Collaboration

International

  • Coeliac Disease Immunochip Consortium, The Netherlands

National

  • Department of Genetics, University of Delhi South Campus, New Delhi, India
  • Department of Rheumatology, All India Institute of Medical Sciences (AIIMS), New Delhi, India
  • Department of Gastroenterology, Dayanand Medical College and Hospital (DMC&H), Ludhiana, Punjab, India
  • Department of Community and Family Medicine, All India Institute of Medical Sciences (AIIMS), Bathinda

Central University of Punjab

  • Dr. Preeti Khetarpal, Department of Human Genetics & Molecular Medicine
  • Dr. Shashank Kumar, Department of Biochemistry
Publications

Articles

 

Communicated

57. Singh H., Saha S., Senapati S*. Unravelling the molecular interactions between Staphylococcus superantigen, susceptibility HLA-DP and T-cell receptor implicated in the onset of granulomatosis with polyangiitis using in silico approach. under review.

56. Singh H., Bhatt R., Verma M., Kakkar R., Banerjee P., Tiwari P., Senapati S*. Community-based estimates for serum Vitamin D, calcium, and phosphorus levels among adults: a quantitative analysis from Punjab. under review. 

55. Vignesh P., Tiwari P., Kaur A., Senapati S*. mRNA expression profile from whole blood revealed a cluster of 25 shared differentially expressed genes inversely related in multiple sclerosis and inflammatory bowel disease. under review. 

54. Tiwari P., Singh O., Joshy L and Senapati S*. Gene expression analyses uncovered the common disease mechanism in celiac disease, rheumatoid arthritis and ulcerative colitis and provided insight into the therapeutic aspects. under review.

53. Sharma N., Duhan D., Gajbhiye S., Rajarammohal S., Baranwal S., Dhekne H. and Senapati S*. Ankyrin-G downregulation in intestinal epithelial cell line mislocalizes E-cadherin resulting in disruption in cellular barrier function. under review. 

 

2024

54. Singh O., Verma M., Dahuya N., Senapati S., Kakkar R., Kalra S. Integrating polygenic risk score (PRS) for personalized diabetes care: advancing clinical practice with tailored pharmacological approaches. Diabetes Ther. 2024. doi: 10.1007/s13300-024-01676-6. (IF: 2.8). 

53. GBD 2021 HIV Collaborators. Global, regional, and national burden of HIV/AIDS, 1990-2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021. Lancet HIV. 2024 Dec;11(12):e807-e822. doi: 10.1016/S2352-3018(24)00212-1. PubMed (IF: 12.8). 

52. Banerjee P., Singh H., Tiwari P., Sood A., Midha V., Singh G., Senapati S*. Assessment of the contribution of vitamin D receptor (VDR) and vitamin-D binding protein (VDBP/GC) genes in celiac disease. Journal of Genetics. 2024. 103, 29. doi.org/10.1007/s12041-024-01480-y. PubMed (IF:1.4). 

51. GBD 2019 MSK in Adolescents Collaborators. Global Pattern, trend, and cross-country inequality of early musculoskeletal disorders from 1990 to 2019, with projection from 2020 to 2050. Med. 2024. 30:S2666-6340(24)00179-X. PubMed (IF:12.8). 

50. GBD 2021 Forecasting Collaborators. Burden of disease scenarios for 204 countries and territories, 2022-2050: a forecasting analysis for the Global Burden of Disease Study 2021. Lancet. 2024. 403(10440):2204-2256. PubMed (IF:168.9)

49. Banerjee, P and Senapati, S*. Translational Utility of Organoid Models for Biomedical Research on Gastrointestinal Diseases. Stem Cell Reviews and Reports. 2024. PubMed (IF: 4.8)

48. GBD 2021 Diseases and Injuries Collaborators. Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2024. S0140-6736(24)00757-8. https://doi.org/10.1016/S0140-6736(24)00757-8. PubMed (IF:168.9)

47. Singh, A., Senapati, S., Panigrahi, I., & Khetarpal, P. Novel Compound Heterozygous Mutations of LIG4 Gene in an Indian LIG4 Syndrome Patient with Severe Microcephaly: Case Report, In-silico Analysis and Systematic Review. Current Pediatric Reviews.   2024.   https://doi.org/10.2174/0115733963285549240328083623. PubMed. (IF: 2.00)

46. GBD 2021 Causes of Death Collaborators. Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2024.S0140-6736(24)00367-2. https://doi.org/10.1016/S0140-6736(24)00367-2. PubMed (IF:168.9). 

45. GBD 2021 Tuberculosis Collaborators. Global, regional, and national age-specific progress towards the 2020 milestones of the WHO End TB Strategy: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Infectious Diseases. 2024. https://doi.org/10.1016/S1473-3099(24)00007-0. PubMed (IF: 56.3) 

44. GBD 2021 Demographics Collaborators. Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950-2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021. Lancet. 2024. S0140-6736(24)00476-8. PubMed (IF:168.9)

43. Pesudovs K., Lansingh VC., Kempen JH., GBD 2019 Blindness and Vision Impairment Collaborators. Global estimates on the number of people blind or visually impaired by cataract: a meta-analysis from 2000 to 2020. Eye (Lond). 2024 Mar 9. doi: 10.1038/s41433-024-02961-1. PubMed (IF: 3.9)

42. Sharma P, Senapati S, Goyal LD, Kaur B, Kamra P, Khetarpal P. Genome-wide association study (GWAS) identified PCOS susceptibility variants and replicates reported risk variants. Archives of Gynecology and Obstetrics. 2024. doi: 10.1007/s00404-024-07400-w. PubMed (IF: 2.6). 

41. Sharma N., Narang V., Sood A., Midha V. and Senapati S*. Reduced expression of Ankyrin-G and E-cadherin in duodenal mucosal biopsy of subjects with celiac disease. Pathology-Research and Practice. 2024. 155164. PubMed (IF: 2.8).

40. Dang S., Jain A., Dhanda G., Bhattacharya N. Bhattacharya A. and Senapati S*. One carbon metabolism and its implication in health and immune functions. Cell Biochemistry and Function. 2024. 42(1):e3926. PubMed (IF: 3.6).

39. Senapati S*., Singh H., Thelma B.K., Verma N., and Kumar U. HLA sequencing identifies novel associations and suggests clinical relevance of DPB1*04:01 in ANCA-associated granulomatosis with polyangiitis. Gene. 2024. 20:896:148024. PubMed (IF: 3.5). 

38. Banerjee P., Sood, A., Midha, V., Narang, V., Grover, J., Senapati S*. A duodenal mucosa transcriptome study identified reduced expression of a novel gene CDH18 in celiac disease. Digestive and Liver Disease. 2024. 56(2):258-264 PubMed (IF:4.5).

37. Sharma P, Kumar Singh A, Senapati S, Singh Kapoor H, Devi Goyal L, Kaur B, Kamra P, Khetarpal P. Genetic Variants of Steroidogenesis and Gonadotropin Pathways and Polycystic Ovary Syndrome Susceptibility: A Systematic Review and Meta-analysis. Metabolism Syndrome and Related Disorders. 2024. 22(1):15-26. PubMed (IF: 2.10)

 

2023 

36. Mensah GA., Fuster V., Murray CJL., Roth G.A., Global Burden of Cardiovascular Diseases and Risks Collaborators. Global Burden of Cardiovascular Diseases and Risks, 1990-2022. Journal of the American College of Cardiology. 2023. 82(25):2350-2473. doi: 10.1016/j.jacc.2023.11.007.PubMed (IF:24). 

35.  Kumar S., Senapati S., Bhattacharya N., Bhattacharya., Maurya SK, Husain H., Bhatti JS. and Pandey AK. Mechanism and recent updates on insulin-related disorders. World Journal of Clinical Cases. 2023. 6;11(25):5840-5856. PubMed (IF:1.10).

34. Dey S.K., Kumar S., Rani, D., Maurya S.K., Banerjee P., Verma M. and Senapati S*. Implications of vitamin D deficiency in systemic inflammation and cardiovascular health. Critical Reviews in Food Sciences and Nutrition. 1-18. doi: 10.1080/10408398.2023.2224880. 2023. PubMed (IF: 11.20).

33. Banerjee P., Chaudhary R., Singh A. K., Parulekar P. P., Kumar S and Senapati S*. Specific genetic polymorphisms contributing in differential binding of gliadin peptides to HLA-DQ and TCR to elicit immunogenicity in celiac disease. Biochemical Genetics. 61(6):2457-2480. doi: 10.1007/s10528-023-10377-x. 2023. PubMed (IF:2.22)

32. Singh H., Kumar U. and Senapati S*. Translational implications of humoral and cellular immune dysfunction in granulomatosis with polyangiitis. Cytokine. 2023.164:156154. PubMed (IF: 3.93) 

31. Shree T., Banerjee P. and Senapati S*. A meta-analysis suggests association of reduced serum level of vitamin D and T-allele of Fok-I polymorphism in vitamin D receptor gene with celiac disease. Frontiers in Nutrition. 2023. 9:996450.PubMed  (IF: 6.59)

30. Singh A. K., Singh S. V., Kumar R., Kumar S., Senapati S. and Pandey A. K. Current therapeutic modalities and chemopreventive role of natural products in liver cancer: Progress and promise. World Journal of Hepatology. 2023. 15(1): 1-18. PubMed (IF: 2.4)

29. Sharma N., Banerjee P., Sood A., Midha V., Thelma B. K. and Senapati S*. Celiac disease associated loci show considerable genetic overlap with neuropsychiatric disease but with limited transethnic applicability. Journal of Genetics. 2023. 102:16. PubMed (IF: 1.4)

 

2022

28. Maurya S. K., Gupta S., Bakshi A., Kaur H., Jain A., Senapati S., Baghel M. S. Targeting mitochondria in the regulation of neurodegenerative diseases: A comprehensive review. Journal of Neuroscience Research. 2022. PubMed (IF: 4.43). 

27. Banerjee, P. Kumar, U. Khetarpal, P. Senapati, S*. Meta-analysis confirmed genetic susceptibility conferred by multiple risk variants from CTLA4 and SERPINA1 in granulomatosis with polyangiitis. International Journal of Rheumatic Diseases. 2022. PubMed (IF: 2.56). 

26. Ghosh, S. Khetarpal, P. Senapati, S*. Functional implications of the CpG island methylation in the pathogenesis of celiac disease. Molecular Biology Reports. 2022. PubMed (IF: 2.74). 

25. Singh, A. Pajni, K. Panigrahi, I. Dhoat, N. Senapati, S. Khetarpal, P. Components of IGF-axis in growth disorders: a systematic review and patent landscape report. Endocrine. 2022 Jun;76(3):509-525. PubMed (IF:3.93). 

24. Prajapati, SK. Singh, AK. Kushwaha, PP. Shauib, M. Gupta, S. Senapati, S. Singh, SP. Kumar, S. Withania somnifera phytochemicals possess SARS-CoV-2 RdRp and human TMPRSS2 protein binding potential: An in silico study. Vegetos. 2022. 1-20. PubMed IIF: _)

 

2021

23. Kumar, S. Singh, AK. Kushwaha, PP. Prajapati, KS. Senapati, S. Mohd, S. Gupta, S. Identification of Compounds from Curcuma longa with In Silico Binding Potential against SARS-CoV-2 and Human Host Proteins Involve in Virus Entry and Pathogenesis. Indian Journal of Pharmaceutical Sciences. 2021. 83 (6), 1181-1195. PubMed  (IF: 0.66)

22. Sharma, N. Singh, K. Senapati, S*. Celiac disease poses significant risk in developing neuropsychiatric diseases: A meta-analysis. Indian Journal of Gastroenterology. 2021. 1-10. PubMed(IF:2.20)

21. Banerjee, P. Jain, A. Kumar, U. Senapati, S*.  Epidemiology and genetics of granulomatosis  with polyangiitis. Rheumatology International. 2021. 41, 2069-2089. PubMed (IF: 3.58)

20. Govindan, R. Banerjee, P. Dhania, NK. Senapati, S*. FTIR based approach to study EnaC mechanosensory functions. Progress in Biophysics & Molecular Biology. 2021. https://doi.org/10.1016/j.pbiomolbio. 2021.07.004. PubMed (IF: 4.80)

19. Bhagavatula, S. Banerjee, P. Sood, A. Midha, V. Thelma, BK. Senapati, S*. Energy metabolism genes with synergistic functions identified in celiac disease. . Journal of Biosciences. 2021. 46:61. PubMed (IF: 2.80). 

18. Maurya, SK. Bhattacharya, N. Mishra, S. Bhattacharya, A. Banerjee, P. Senapati, S. Mishra, R. Microglia specific drug targeting using natural products for the regulation of redox imbalance in neurodegeneration. Frontiers in Pharmacology. 2021. 12:654489. PubMed (IF:5.98).  

17. Senapati, S*. Banerjee, P. Bhagavatula, S. Kushwaha, PP. Kumar, S. Contributions of human ACE2 and TMPRSS2 in determining host-pathogen interaction in COVID-19. Journal of Genetics. 2021.100:12. PubMed  (IF: 1.4). 

 

2020

16. Bhattacharya, N. Maurya, SK. Senapati, S*. Bhattacharya, A. Drug repurposing: A strategy to treat human coronavirus disease (COVID-19). International Journal of Tropical Disease & Health. 2020. 41 (21), 42-54. Article(IF: --). 

15. Sharma, N. Bham, K. Senapati, S*. Human Ankyrins and their contribution in disease biology: A Recent Update. Journal of Biosciences. 2020. 45:146. PubMed  (IF:2.80). 

14. Senapati, S*. Kumar, S. Singh, AK. Banerjee, P. Bhagavatula, S. Assessment of risk conferred by coding and regulatory variants of TMPRSS2 and CD26 in susceptibility of SARS-CoV-2 infection in human. Journal of Genetics. 2020. 99(1):53. PubMed (IF:1.51). 

13. Gupta, S. Singh, AK. Kushwaha, PP. Prajapati, KS. Shuaib, M. Senapati, S. Kumar S. Identification of potential natural inhibitors of SARS-CoV2 main protease by molecular docking and simulation studies. Journal of Biomolecular & Structural Dynamics. 2020. 11:1-12. PubMed (IF:5.24). 

 

2019

12. Banerjee, P. Bhagavatula, S. Sood, A. Midha, V. Thelma, BK. Senapati, S*. Association study identified biologically relevant receptor genes with synergistic functions in celiac disease. Scientific Reports. 2019. 9(1):13811. PubMed(IF:5.00).  

11. Khanna, R. Nandy, D. Senapati, S*. Sysematic review and meta-analysis to establish the association of common genetic variations in vitamin D binding protein with chronic obstructive pulmonary disease. Frontiers in Genetics. 2019. 10:413. PubMed  (IF: 4.77). 

10. Nandy, D. Sharma, N. Senapati, S*. Systematic review and meta-analysis confirms significant contribution of surfactant protein D in chronic obstructive pulmonary disease. Frontiers in Genetics. 2019. 10:339. PubMed(IF: 4.77).  

9. Chaudhary, D. Sharma, N. Senapati, S*. Serum homocysteine could be used as a predictive marker for chronic obstructive pulmonary disease: A Meta-analysis. Frontiers in Public Health. 2019. 7:69. PubMed (IF: 6.46). 

 

2018

8. Marquez, A. Kerick, M. Coeliac Disease Immunochip Consortium. et al. Meta-analysis of Immunochip data of four autoimmune diseases releals novel single-disease and cross-phenotype associations. Genome Medicine 2018. 20;10(1):97.PubMed  (IF:15.27). 

 

2016

7. Senapati, S. Sood, A. Midha, V. Sood N. Sharma, S. Kumar, L. Thelma B.K. Shared and unique genetic determinants between pediatric and adult celiac disease. BMC Medical Genomics, 2016, 9(1):44. PubMed(IF: 3.62). 

 

2015

6. Senapati, S. Gutierrez-Achury, J. Sood, A. Midha, V. Szperl, A. Romanos, J. Zhernakova, A. Franke, L. Thelma, B.K. Wijmenga, C. Trynka, G. Evaluation of European coeliac disease risk variants in a North Indian population. European Journal of Human Genetics, 2015;23(4):530-5. PubMed (IF: 5.35). 

5. Juyal, G. Negi, S. Sood, A. Senapati, S. Gupta, A. Prasad, P. Singh, S. Zaneveld, J. Midha, V. van Sommeren, S. Weersma, R.K. Ott, J. Jain, S. Juyal, R.C. Thelma, B.K. Genome-wide association scan in a north Indian cohort identifies three novel HLA independent susceptibility loci in ulcerative colitis.  Gut, 2015;64(4):571-9.  PubMed(IF: 31.79).

 

2014

4. Senapati, S. Singh, S. Das, M. Kumar, A. Gupta, R. Kumar, U. Jain, S. Juyal, R.C. Thelma, B.K. Genome-wide analysis of methotrexate pharmacogenomics in rheumatoid arthritis reveals novel risk variants and leads for TYMS regulation. Pharmacogenetics and Genomics, 2014:24(4):211-9. PubMed (IF: 2.00).

 

2013

3. Negi, S. Juyal, G. Senapati, S. Prasad, P. Gupta, A. Singh, S. Kashyap, S. Kumar, A. Kumar, U. Gupta, R. Kaur, S. Agrawal, S. Aggrawal, A. Ott, J. Jain, S. Juyal, R.C. Thelma, B.K. A genome-wide association study reveals ARL15, a novel non-HLA susceptibility gene for Rheumatoid arthritis in north Indians. Arthritis & Rheumatology, 2013;65(12):3026-35. PubMed (IF: 15.48).  

 

2011

2. Trynka, G. Hunt, K.A. Bockett, N.A. Romanos, J. Mistry, V. Szperl, A. Bakker, S.F. Bardella, M.T. Bhaw-Rosun, L. Castillejo, G. de la Concha, E.G. de Almeida, R.C. Dias, K.R. van Diemen, C.C. Dubois, P.C. Duerr, R.H. Edkins, S. Franke, L. Fransen, K. Gutierrez, J. Heap, G.A. Hardlickova, B. Hunt, S. Plaza Izurieta, L. Izzo, V. Joosten, L.A. Langford, C. Mazzilli, M.C. Mein, C.A. Midha, V. Mitrovic, M. Mora, B. Morelli, M. Nutland, S. Nunez, C. Onengut-Gumuscu, S. Pearce, K. Platteel, M. Polanco, I. Potter, S. Ribes-Koninckx, C. Ricano-Ponce, I. Rich, S.S. Rybak, A. Santiago, J.L. Senapati, S. Sood, A. Szajewska, H. Troncone, R. Varadé, J. Wallace, C. Wolters, V.M. Zhernakova, A. Spanish Consortium on the Genetics of Coeliac Disease (CEGEC). PreventCD Study Group. Wellcome Trust Case Control Consortium (WTCCC). Thelma, B.K. Cukrowska, B. Urcelay, E. Bilbao, J.R. Mearin, M.L. Barisani, D. Barrett, J.C. Plagnol, V. Deloukas, P. Wijmenga, C. van Heel, D.A. Dense genotyping identifies and localizes multiple common and rare variant association signal in celiac diseases. Nature Genetics, 2011; 6;43(12):1193-201. PubMed(IF: 41.31). 

1. Juyal, G. Prasad, P. Senapati, S. Midha, V. Sood, A. Amre, D. Juyal, R.C. Thelma, B.K. An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians. PLoS ONE, 2011; 6(1): e16565.PubMed (IF: 3.75) 

PubMed    Google Scholar 

 

                               Total citations                h-index:              i10 index

 Google scholar:     2304                                 19                         27

 

 

 ORCID ID: https://orcid.org/0000-0002-9448-7432

Book Chapters

  1. Dey, S.K., Senapati, S*. (2021). In Vivo Models for Obesity and Obesity Related Carcinogenesis. In: Kumar, S., Gupta, S. (eds) Obesity and Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-16-1846-8_14

  2. Bhattacharya, N., Maurya, S.K., Bhattacharya, A., Senapati, S*. (2021). Obesity-Induced Chronic Low-Level Inflammation and Cancers. In: Kumar, S., Gupta, S. (eds) Obesity and Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-16-1846-8_1

  3. Dey, S.K., Senapati, S*. (2021). Insulin and Insulin-Like Growth Factor-1 Associated Cancers. In: Kumar, S., Gupta, S. (eds) Obesity and Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-16-1846-8_3

  4. Maurya, S.K., Bhattacharya, N., Bhattacharya, A., Senapati, S*. (2021). Adipokines Play Important Role in Cell Proliferation and Anti-proliferation. In: Kumar, S., Gupta, S. (eds) Obesity and Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-16-1846-8_4

  5. Biswas, I., Maurya, S.K., Senapati, S*. (2021). mTOR and AMP-Activated Protein Kinase in Obesity and Cancer. In: Kumar, S., Gupta, S. (eds) Obesity and Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-16-1846-8_5

  6. Bhattacharya, A., Sharma, N., Bhattacharya, N., Senapati, S*. (2019). In-silico Targets in Immune Response. In: Kumar, S., Egbuna, C. (eds) Phytochemistry: An in-silico and in-vitro Update. Springer, Singapore. https://doi.org/10.1007/978-981-13-6920-9_21

  7. Sharma, N., Dhekne, H.S., Senapati, S*. (2019). Immunomodulatory Potential of Phytochemicals: Recent Updates. In: Kumar, S., Egbuna, C. (eds) Phytochemistry: An in-silico and in-vitro Update. Springer, Singapore. https://doi.org/10.1007/978-981-13-6920-9_8

  8. Senapati, S*. (2017). Alternative Pathways for Glucose Metabolism. Nova Science Publishers. USA. ISBN.978-1-53612-907-6

Popular Science Articles 

  1. Personalized medicine: A hope for better public health. October. 2015. NE Scholar Magazine
  2. Vaccine Development: Trials, Approval Process and Ethical Issues. December 2020. Dream 2047. Vigyan Prasar
  3. Folic acid must for healthy and safe pregnancy. March, 2021. Dream 2047. Vigyan Prasar

 

Research Guidance

PhD

Fellow Fellowship Research Focus Current status
Nidhi Sharma DST-Women Scientist- A  Genetic Investigation and functional analysis of susceptibility loci associated with celiac disease.  2017- 2023 (awarded)
Pratibha Banerjee DST INSPIRE Fellow Investigation of small intestinal tissue-specific gene expression regulation in celiac disease

2020-2024 (submitted)
Priyanka Tiwari CSIR - SRF Celiac disease genetics and functional genomics 2021-ongoing 
Harinder Singh Project - JRF Genetics and genomics of granulomatosis with polyangiitis  2021-ongoing

Annu

 UGC Fellow Yet to be decided 2023-ongoing 

 

PhD student achievements
     PhD Fellow                                  Recognition/Award
Nidhi Sharma
  • Young Researcher Award (Medical & Health Science) at 1st National Biomedical Research Competition, October 2018, AIIMS Rishikesh. 
  • Best Presentation Award (Life Science) at 4th National Biomedical Research Competition, December 2023, MCH, Alwar.
Pratibha Banerjee
  • Chancellor's Award for Best PhD student at Central University of Punjab, Bathinda. 2024. 
  • Best Presentation Award (Health Science) at 5th National Biomedical Research Competition, December 2024, AIIMS, New Delhi.
Harinder Singh
  • 3rd Prize, Poster Presentation Award (Health Science) at 5th National Biomedical Research Competition, December 2024, AIIMS, New Delhi. 
   

 

Project Fellow

  • Harinder Singh - ICMR Project JRF

M.Sc Dissertation Thesis 

  • 49 students (2015-2023)

Summer Internship 

  • Deepika Krishnamoorthy (IAS Summer Fellow-2023)
  • Simran Lawrance (IAS Summer Fellow-2021)
  • Pratima Parulekar (2020)

Laboratory Alumni Placement

Sn

Alumni Name

Year of Graduation

National Level Test

Current Position
1. Dr. Nidhi Sharma 2023 (PhD) CSIR-NET Post Doctoral Fellow at PGIMER, Chandigarh

2.

Ruchika Maurya

2017

CSIR -JRF

PhD from National Agri- Food Biotechnology Institute, Mohali, India

3.

Abhishek Singh

2017

GATE

Data Scientist, University of Liverpool, UK

4.

Ritesh Khanna

2018

GATE

PhD from University of South Bohemia, Czech Republic

5.

Kamlesh Bham

2018

GATE

Senior Associate in WNS Global Services, Mumbai, India

6.

Deepti Chaudhary

2018

-

Genetic Counselor at LifeCell International Pvt. Ltd. Chandigarh

7.

Debparna Nandy

2018

ICMR SRF, CSIR NET

PhD from Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram, Kerala

8.

Sandilya Bhagavatula

2019

DBT-JRF, GATE

Pursuing PhD from Translational Health Science and Technology Institute (THSTI), Faridabad, India

9.

Pratibha Banerjee

2019

DST Inspire, GATE

Pursuing PhD from Central University of Punjab, Bathinda

10.

Yogender

2019

GATE

Teaching at Allen Career Institute

11.

Souparni Ghosh

2020

CSIR NET, GATE

Research Fellow at National Centre for Cell Science (NCCS), Pune.

12.

Anand Anunay

2020

GATE

Pursuing PhD at CSIR-National Botanical Reseach Institute, Lucknow.

13.

Malavika Menon

2020

GATE

Pursuing PhD from Institute of Biology, Freie University Berlin, Germany 

14.

Aditi Rani

2021

-

Genetic Counselor at INDx Technology, Pvt. Ltd.

15.

Wansana P Khongjee

2021

-

Intern at Open Health Systems Laboratory (OHSL), USA
16. Shikha Gorke 2021 GATE, CSIR-JRF Pursuing PhD from CSIR-IIIM, Jammu
17. Shreya Dang 2022 GATE, DBT-JRF

Pursuing PhD from IISER, Bhopal
18. Tanya Shree 2022 GATE

Data analyst at MedGenome, Bangalore
19. Soofiya Samad 2022 GATE

Pursuing PhD from Central University of Hyderabad, Hyderabad
20. Liya Joshy 2023 GATE Pursuing PhD from Kasturba Medical College of Manipal University.
21. Omna Singh 2023 - Genome Analyst, MedGenome, Bangalore.
22. Sohini Saha 2023 - Genome Analyst, MedGenome, Bangalore.
23. Gargi Kumari 2024 - Genome Analyst, MedGenome, Bangalore.
24. Annesha Roy 2024 - Genome Analyst, MedGenome, Bangalore.

# laboratory alumni may contact us to update their present employment/position 

 

Conference/ Workshops/Seminars Attended

Orientation and Refresher Courses

  • NEP Orientation & Sensitization Programme. June 03 - June 11, 2024. MMTTC, Guru Nanak Dev University, Amritsar. 
  • 1st Short Term Course in Entrepreneurship, Innovation and Start-Ups. August 23 – August 28, 2021. UGC-HRDC, Jawaharlal Nehru University, New Delhi, India.
  • Online Two-Week Inter-Disciplinary Refresher Course/Faculty Development Programme of “Advanced Research Methodology Tools and Thechniques”. April 15 – April 30, 2021. PMMMNMTT Teaching Learning Centre, Ramanujan College, University of Delhi, New Delhi, India
  • Two Week Online Faculty Development Programme on “Managing Online Classes and Co-Creating MOOCS 3.0”. July 25 – August 10, 2020. PMMMNMTT Teaching Learning Centre, Ramanujan College, University of Delhi, New Delhi, India
  • Science Academies’ Refresher Course on “Plant Taxonomy, Phytogeography and Ecology”. March 05 – March 20, 2019. Central University of Punjab, Bathinda, Punjab, India
  • UGC-Sponsored “Orientation Programme”. November 13 – December 10, 2018. UGC-HRDC, Punjab University, Chandigarh, India

Workshops/Trainings

  • Training Program on "Good Clinical Practice (GCP)". Shodh Clinicals. 10th August, 2024. 
  • Innovation Ambassador training (Foundation Level). Ministry of Education's Innovation Cell & AICTE. June 30 - July 30, 2021. 
  • Genetic Epidemiological Research and Data Analysis. May 23-27, 2011. By Graduate School for Drug Exploration. University Medical Center Groningen, The Netherlands
  • International course on Epidemiological Methods. Organized by International Epidemiological Association. April 5-7, 2009. Jaipur, India
  • Genetic Epidemiological Methods for Dissection of Complex Human Traits. Organized by TCG-ISI Centre for population genetics, Kolkata and University of Pittsburgh, Pittsburgh, U.S.A. Feb. 23-28, 2009. Kolkata, India 

Conferences and Symposiums

  • 48th Annual Meeting and International Conference of the Indian Society of Human Genetics (ISHG). January 21-24, 2024. Institute of Human Genetics, Ahmedabad, Gujarat. 
  • 47th Annual Conference of the Indian Society of Human Genetics (ISHG) & International Symposium on "New Genetics and its Contributions to Human Health and Wealth. January 23 - 25. 2023. Andhra University, Visakhapatnam. 
  • International Webinar on “Prospects of Natural Products on Human Health in Current Scenario”. June 24, 2020. Department of Botany, Banaras Hindu University, Varanasi, India
  • “International COVID-19 Conference”. May 15, 2020. Stanford Center for Continuing Medical Education, Stanford, CA, USA
  • 44th Annual Conference of the Indian Society of Human Genetics on “Genomics for Health and Precision Medicine”. Jan. 30th-Feb. 1st 2019. NIBMG & University of Kalyani, West Bengal. India
  • 1st National Biomedical Research Competition. October 15. 2018. AIIMS, Rishikesh, India
  • Recent Advances in Molecular Genetics With New Biomedical Insights. An Indi-Israel Meeting. February 12-13. 2018. Indian National Science Academy (INSA), New Delhi, India
  • 17th International Celiac Disease Symposium. Sept. 8-10. 2017. Le Meridean, New Delhi, India
  • 42nd Annual Meeting of the Indian Society of Human genetics & International Symposium on Trends in Human Genetic Research & Management. March 2-4. 2017. Indian Institute of Science, Bengaluru, India
  • The 13th International Congress of Human Genetics. April 3-7, 2016. Kyoto International Conference Center, Kyoto, Japan
  • 7th Annual Convention of Association of Biotechnology and Pharmacy & International Conference on Plant Biotechnology, Molecular Medicine & Human Health. October 18-20, 2013. University of Delhi South Campus. New Delhi. India
  • National Science Day Symposium-2013. February 27-28, 2013. University of Delhi South Campus, New Delhi
  • International conference on Genes, Genetics and Genomics: Today and Tomorrow-Human concerns and XXXVII annual conference of The Indian Society of Human Genetics. March 3-5, 2012. Panjab University, Chandigarh, India
  • National Science Day Symposium-2012. February 27-28, 2012. University of Delhi South Campus, New Delhi
  • 12th International Congress of Human Genetics & 61st American Society of Human Genetics. October 11-15, 2011. Montreal, Canada
  • International Networking Conference: From DNA to Phenotype. March 9 – 11, 2011. Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
  • International conference on Molecular and Clinical aspects of Gonadal and Non-gonadal actions of Gonadotropins. February 7-9, 2008. New Delhi. India. Organized by Department of Reproductive Biology, All Indian Institute of Medical Sciences, New Delhi, India
  • 30th All Indian Cell Biology Conference & Symposium on Molecules to Compartments: Cross-Talk and Networks. February 2-4, 2007. New Delhi. India. Organized by Department of Zoology, University of Delhi and Indian Society of Cell Biology

Meetings

  • Regional Meet organized by Institutios' Innovation Council, MoE's Innovation Cell. November 21. 2023. Panjab University, Chnadigarh. 
  • 6th National IBD Meet on IBD. September 15-16, 2018. Convention Centre, Hotel Pullman, New Delhi. Organized by Colitis and Crohn’s Foundation (India)
  • 3rd National IBD Meet on IBD in different ethnic groups: East vs. West? September 29-30, 2012. Gurgaon, Haryana, India. Organized by Colitis and Crohn’s Foundation (India)
  • 2nd National IBD Meet on Understanding the enigma of IBD in India. May 23, 2010. New Delhi, India. Organized by Colitis and Crohn’s Foundation (India)
  • Satellite meeting of HGM 2008 on Clinical Genomics. September25, 2008. New Delhi, India. Organized lby Indian Council for Medical research
Conference/ Workshops/Seminars Organised

Workshop

  • Organizing Member. DST PURSE sponsored "Two Days Workshop on EVOS M7000 Microscope". 21-22 November, 2024. Central University of Punjab, Bathinda. 
  • Organizing Member. DST PURSE sponsored National Conference on "Emerging Trends in Cancer Prevention and Therapeutic Interventions". 26-27 September, 2024. Central University of Punjab, Bathinda. 
  • Organizing Secretary. “Basics of Next Generation Sequencing and Protein Modelling”. March 30th, 2021. Central University of Punjab, Bathinda
  • Organizing Member. DBT-Sponsored Training Course in Medical Genetics and Bioinformatics. March 9-23, 2016. Central University of Punjab, Bathinda, India
  • Organizing Secretary. Workshop on Model Organisms in Molecular Genetic Research. March 21, 2016. Central University of Punjab, Bathinda, Punjab

Conference/Seminar/Symposium

  • Organizing Member and coordinator. Seminar on "Prenatal and Postnatal diagnosis of genetic disorders”. October 23rd, 2021. Central University of Punjab, Bathinda
  • Organizing Member. “Indian Traditional Medicine in Cancer Therapy and Prevention”. February 4th, 2020. Central University of Punjab, Bathinda
  • Organizing Member. “Expert Lectures on Cancer Prevention and Awareness”. February 3rd, 2020. Central University of Punjab, Bathinda
  • Organizing Secretary. Special lectures on “Genomic Medicine” & Workshop on “Molecular Modelling & Developmental Genetics”. March 24-25, 2017. Central University of Punjab, Bathinda, Punjab

 

NSS Activities

    • Coordinator (NSS Program Officer). "Constitution Day". November, 26th, 2021. Central University of Punjab, Bathinda. 
    • Coordinator (NSS Program Officer). "NSS Day". September, 24th, 2021. Central University of Punjab, Bathinda. 
    • Coordinator (NSS Program Officer). "Polycystic Ovarian Syndrome awareness program". September, 14th, 2021. Central University of Punjab, Bathinda. 
    • Coordinator (NSS Program Officer). "World Yoga Day event on Art of Living". June, 17th - 19th, 2021. Central University of Punjab, Bathinda. 
    • Coordinator (NSS Program Officer). "World No Tobacco Day". May 31st, 2021. Central University of Punjab, Bathinda
    • Coordinator (NSS Program Officer). "World Health Day". April, 7th, 2021. Central University of Punjab, Bathinda.
    • Coordinator (NSS Program Officer). "International Women's Day". March, 8th, 2021. Central University of Punjab, Bathinda. 
    Invited Talks/ Resource Person
    11. Invited talk on "Skill based Education: NEP-2020 and beyond". January, 10, 2024. Two Weeks Refresher Course by "Malaviya Mission Teacher Training Centre (MMTTC)" at Central University of Punjab, Bathinda. India.
    10. Invited talk on "The evolution of genetic diagnosis techniques" December, 14-17th. 52nd Annual Conference of the Endocrine Society of India & 6th Biennial SAFES International Endocrine Summit. HICC Novotel. Hyderabad, India.
    9. Invited talk on "Careers for science graduate". September 9th, 2023. IQAC and Department of Zoology, Ramjas College, University of Delhi, Delhi. India.
    8. Invited talk in "5th International Conference on Nutraceuticals and Chronic Diseases". October 7-9, 2022. University of Delhi, India.
    7. Invited talk in International Webinar on “Post-COVID challenges and opportunities for the Chemist”. December 28, 2021. University of Delhi and Indian Science Congress Association, Delhi.
    6. Invited talk in National Webinar on “COVID-19 and Our Coexistance” June 4, 2021. Gopichand Arya Mahila College, Panjab University, Abohar, Punjab
    5. Invited talk in National Symposium on “Recent Trends and Ethics in Biological Research” March 7, 2020. Dyal Singh College, University of Delhi, New Delhi
    4. Invited talk in 2nd National Seminar on “Responsible Research and Innovations in Science & Technology” (RRIST-2020), February 29, 2020. Guru Nanak College, Punjabi University, Budhlada, Punjab
    3. Talk on “Genome-wide association study identified several novel genes and BMP associated pathways with bone erosion in rheumatoid arthritis” at 44th Annuam Conference of Indian Society of Human Genetics. Jan 31st-1st feb, 2019. Kalyani University, West Bengal. India
    2. Lecture on “Strategies for Linkage and Association mapping”, at DBT-Sponsored Training Course in Medical Genetics and Bioinformatics. March 9-23, 2016. Central University of Punjab, Bathinda, India
    1. Lecture on “Introduction to Biostatistics”, at DBT-Sponsored Training Course in Medical Genetics and Bioinformatics. March 9-23, 2016. Central University of Punjab, Bathinda, India
    Patent Filed/ Published
     
     
     
    Community Participation
    Community services within and around the University campus at Bathinda (as NSS program officer)
    Curricular Development
    Development and continuous modification of M.Sc and PhD Human Genetics course
    HGE.509 Biostatistics and Research Methodology
    HGE.512 Biostatistics and Research Methodology-Practical
    HGE701 Research Methodology & Biostatistics (PhD Course Work)
    HGE.510 Concepts of Genetics
    HGE.513 Concepts of Genetics -Practical
    HGE.527 Human Embryology & Developmental Genetics
    HGE.528 Population Genetics & Genetic Epidemiology
    HGE.551 Pharmacogenomics & Nutrigenomics
    HGE.553 Recombinant DNA Technology & Therapeutics
    HGE.554 Tools in Bioinformatics-Practical
    Other Significant Achievements

    News paper articles on Laboratory work

    Vitamin D deficiency screening and awareness
    Vitamin D deficiency screening and awareness
    lab
    Community outreach for vitamin d deficiency screening and awareness

     

     

    Swatchhata Pakhwada 2022

    Swatchata Pakhwada Celebration, 2022 

     

     

    World Heart Day 2022

    Hands-on CPR training on World Heart Day, 2022