Department of Pharmaceutical Sciences and Natural Products
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Project Completed
Centre for Pharmaceutical Sciences and Natural Products (formerly known as Centre for Chemical and Pharmaceutical Science) was established in 2011. At present the centre has two well established research labs with a number of sophisticated research instruments, such as, microwave synthesizer, solid phase peptide synthesizer, solvent extractor, flash chromatography, monochromatic micro palate reader and many more. The main motto of the centre is to conduct research on cancer and to find out a recognized drug in overcoming this disease which is a major problem in this Malwa region, causing higher rates of cancer incidence. Currently the centre has highly qualified faculty and also organizes from time to time guest faculty lecturesfor the benefit of the students and to create awareness for the recent trends followed in medicinal chemistry research worldwide. The center has also achieved research grants from pioneer funding agencies like DST and UGC, in the form of DST-FastTrack, UGC-Major Project and UGC start up grant and own university grant (RSM). Besides this many research/review papers are being continuously published in various pioneer national and international journals which all speak about the excellence of the centre. The centre is currently following the latest trends and conducting a thorough research on Design, Synthesis and Biological Screening of Novel Multi-target inhibitors of Tyrosine Kinase(s) and Topoisomerase, Synthesis of Bioactive Heterocyclic Scaffolds Using Novel Green Technologies and Synthesis of Rebaudioside-A: Natural Substitute for Sugar from Stevia rebaudiana (Bertoni) and many more.
Invited/Guest Lectures at the Centre
Lecture by Mr. Donald Bouchard, USA on “Instrumentation and Applications of 90 Hz NMR” on 18-09-2015.
Lecture by Prof. V.K. Kapoor, former Chairman, UIPS, Panjab University Chandigarh on “Understanding stereochemistry at grass root level” on 05-10-2015.
Keynote adress by Prof. P.V. Bharatam, NIPER, Mohali on “New concepts in chemical bonding leading to the design of anti-malarial agents” during three day workshop on Drug Design, Molecular Docking, Virtual Screening and Pharmacoinformatics on 26-11-2015.
Lecture by Dr. Brahmam Pujala, Integral Biosciences on “Small Molecule Kinase Inhibitors: Challenges and Opportunities” on 22-12-2015
Lecture by Dr. Hemant Bhutani, Biocon Bristol-Myers Squibb R&D Centre (BBRC), Bangalore on “Analytical Sciences in Drug Discovery and Development” on 01-02-2016
Lecture by Professor K. L. Dhar, Former Head, Natural Product Division, IIIM, Jammu on “Basics of NMR and its spectral interpretations” and “Terpenoids as Medicines” on 26-08-2016.
Lecture by Professor Uttam Chand Banerjee, NIPER, Mohali on “Use of nanobiocatalysts as enzyme source for the synthesis of chiral drugs and drug intermediates ” and “Process development for the production of rifamycin oxidase and subsequent hydrolysis of rifamycin B to rifamycin S by Curvularia lunata” on 04-09- 2017
Dr. Hemant Butani, Head Analytical Division, BMS, Bangalore Based -Delivered a Lecture on “Importance of Solid State Characteristics of Impurities” at Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda on January 25, 2018
Dr. Narinder Singh, Associate Professor IIT Ropar, Delivered a Lecture on “Artificial Receptors for Sustainable Development and Biological Applications” at Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda on March 31, 2017
Dr. Santosh Rudrawar, Lecturer, School of Pharmacy and Pharmacology, Griffith University, Australia-Delivered a Lecture on “Chemical Probes as Tools to Study Carbohydrate-processing Enzymes” at Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda on January 22, 2018
Prof. T. R. Bhardwaj, Dean School of Pharmacy and Emerging Sciences Baddi University of Emerging Sciences and Technology Baddi, Solan(HP)-Delivered a Lecture on “ Medical Significance of Novel Polymer-Linked Prodrugs in the Target Specific Drug Delivery” at Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda on January 25, 2018
Activities
The Centre organized a three day workshop on “Drug Design, Molecular Docking, Virtual Screening and Pharmacoinformatics” in association with Schrödinger INC. USA from 26-11-2015 to 28-11-2015. Fourty participants from 14 different Universities/Institutes of north India were selected out of 64 applications received.
A glimpse of various activities during workshop.
The Department organized a three day workshop on “ADVANCED WORKSHOP ON MOLECULAR DOCKING, VIRTUAL SCREENING AND COMPUTATIONAL BIOLOGY” in association with Schrödinger INC. USA from 15-11-2017 to 17-11-2017. Forty three participants from different Universities/Institutes of north India and Nepal attended the workshop.
Awards
Professor P. Ramarao was awarded Dr. K.M. Parikh Award at International Conference on “Challenges for Global Competitiveness of AYUSH and Natural Products” held at Delhi Institute of Pharmaceutical Sciences and Research University (DPSRU) organized jointly in collaboration of the International Association for the Study of Traditional Asian Medicines (IASTAM) and Delhi Pharmaceutical Sciences and Research University on February 2-4, 2018.
Dr. Raj Kumar from Centre for Pharmaceutical Sciences and Natural Products has got research award (2014-15) from Honourable Chancellor of Central University of Punjab, Bathinda on dated 28th Feb, 2016.
Dr. Vikas Jaitak from Centre for Pharmaceutical Sciences and Natural Products has got research award (2014-15) from Honourable Chancellor of Central University of Punjab, Bathinda on dated 28th Feb, 2016.
Mr. Gaurav Joshi receiving Sun Pharma Science Scholar Award-2017 under the category of Pharmaceutical Sciences on the research work entitled "Targeting chromatin coupled enzymes by small molecules in cancer cells" at India Habitat Centre, under the aegis of Sun Pharma Science Foundation, Gurugram on 12 February 2018. The award consists of a glass engraved certificate and cash prize of Rs. 50,000.
Faculty
Academic Programmes Offered
Syllabi
Our Alumini
Board of Studies
Research at Glance
The centre is currently engaged with developing small novel dual inhibitors as anticancer agents pertaining to inhibit Epidermal Growth Factor Receptors, Histone Deacetylases and Topoisomerase 1 and 2 which are most frequently overexpressed in many forms of cancers. Further studies on small molecule heterocyclics as novel potential drug candidates and hybrid/multi-targeted pharmacophoric drug approaches to withhold the issue of resistance emergence in DNA damaging chemotherapy, project studies of design and development of DNA repair enzyme inhibitors are also carried out. The center is also working on synthesis of small molecules using green chemistry approach and also on the designing of small molecule for Colchicine binding sites. In addition to working on the field of cancer, centre is also working on development of small molecule for Alzheimers and other neuronal diseases by targeting the monoamine oxidase inhibitors. Diabetes mellitus is one of the most 25 prevalent diseases around the world; the center focuses on the development of synthetic sugar substitute inspired from nature. In short, the centre is poised to meet the challenges and demand for world class medicinal chemists to carry out the drug design and discovery. The programmes in medicinal chemistry have been initiated to increase capacity building and to produce innovative medicinal chemists. Presently research is being carried out in discovery of anticancer, antidiabetic and antigout agents utilizing natural products or synthetic and semi synthetic approaches.
Laboratory Facilities
Centre for Pharmaceutical Sciences and Natural Products Laboratory is equipped with well furnished chemical resistant furniture and many sophisticated international standard instruments such as Microwave synthesizer, Lab Willy Grinder, Camera Lucida Muffle Furnace, Digital colony counter , Moisture Determination balance, Safety control heating plate with stirrer and BUCHI speed extractor 914.
Publication
Patent:
Title: Novel fused heterocycles and method of use and manufacture thereof. Inventors: Kumar, R., Singh, S,. Chauhan, M. Indian Patent application no. 201611014161 filed on April 22, 2016.Papers Presented in Seminars/Conferences/Symposia/Workshops
List of the Projects Approved During the Year
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